-ART I • BASIC ASPECTS OF HYBRID IMAGING TECHNOLOGY // Radiation Sources for Emission Scanning: Dositron and Gamma Emission 9 // v nstantinos Zeimpekis // - ET Scanning: Principles and Instrumentation 15 // Joshua D. Schaefferkoetter and David W. Townsend // SPEC! Scanning: Principles and Technologic Options 26 // David R. Gilland and Timothy G. Turkington // Basics of CT Scanning and Issues Relevant to Hybrid Imaging 33 // Willi A. Kalender // MR Scanning: Principles Relevant to Hybrid Imaging 39 // Oliver Kraff, Marcel Gratz, Karsten Beiderwellen, and Mark E. Ladd // Attenuation Correction for Emission Scanning 50 // Ciprian Catana and David W. Townsend // Options in Image Reconstruction in Hybrid Imaging 64 // Charles Stearns // Image Coregistration and Coregistered Image Rendering 71 // Cyrill Burger and Geoffrey Warnock // Quantifying PET and SPECT 81 // Cyrill Burger, Alfred Buck, Timothy G. Turkington, Geoffrey Warnock, and David R. Gilland // ’0 Standardizing PET and SPECT for Quantitative Imaging 89 // Paul Kinahan // Minimizing Radiation Dose in Hybrid Imaging 96 // Konstantinos Zeimpekis and Gašpar Delso // 12 A Primer in Compartment Modeling 103 // Cyrill Burger and Alfred Buck // PART II • RADIOPHARMACEUTICALS // 13 Clinical PET Radiopharmaceuticals Based on 18Fluorine 115 // Linjing Mu, Anass Johayem, Gustav K. von Scbulthess, and Simon M. Ametamey // 14 Clinical PET Radiopharmaceuticals Prepared // from Cyclotron-Produced Positron Emitters Other Than Fluorine
18 123 // K]ell Nägren and Christer Halldin // 15 Clinical PET Radiopharmaceuticals Produced by Generators 130 // Jakub Šimecek and Hans-Jürgen ’Wester // 16 Clinical SPECT Radiopharmaceuticals 134 // Martin ? ehe, Gerrit Wester a, and Roger Schibli // PART III • CLINICAL HYBRID IMAGING OF THE BRAIN // 17 The Normal Brain Scan: Appearance and Data Analysis 143 // Alfred Buck and Geoffrey Warnock // 18 Cerebrovascular Disease 149 // Alfred Buck and Nadja Khan // 19 Brain Tumors: Astrocytoma, Oligodendroglioma, and Glioblastoma 159 // Karl-Josef Langen, Norbert Galldiks, // Lutz Kracht, Andreas H. Jacobs, and Karl Herholz // 20 Brain Tumors: Other Primary Brain Tumors, Metastases, and Radiation Injury 169 // lan Law and Liselotte Hojgaard // 21 Infections of the Central Nervous System 180 // Alfred Buck and Michael Sommerauer // 22 Epilepsy 186 // Alfred Buck and Michael Sommerauer // 23 Neurodegenerative Disease: Protocols, Normal Findings, and Pitfalls 193 // Alexander Drzezga // 24 Dementia 197 // Christoph Hock, Anton Gietl, Alfred Buck, and Alexander Drzezga // 25 Movement Disorders 210 // Klaus Tatsch // 26 Pediatrie Hybrid Imaging of the Brain 218 // Ian Law, Lise Borgwardt, and Liselotte Hojgaard // PART IV • CLINICAL MULTIMODALITy IMAGING OF THE HEART // 27 Protocols, Data Analysis, Normal Scans, and Pitfalls in the Heart 233 // Ronny R. Buechel and Philipp A. Kaufmann // 28 Coronary Artery Disease: Perfusion 241 // Aju P. Pazhenkottil, Oliver Gaemperli, and Philipp
A. Kaufmann // 29 Coronary Artery Disease: Tissue Viability and Perfusion 250 // Markus Schwaiger and Stephan G. Nekolla // 30 Noncoronary Cardiac Disease 266 // Frank Bengel // PART V • CLINICAL HYBRID IMAGING IN BODY ONCOLOGY // PROTOCOLS, NORMAL FINDINGS, ARTIFACTS, AND PITFALLS // 31 Artifacts in Hybrid Extended Region Scans 279 // Gustav K. von Schulthess and Gašpar Delso // 32 FDG Hybrid Imaging: Protocols, Normal Scans, and Pitfalls 288 // Gustav K. von Schulthess // 33 Basics of Molecular Imaging of Prostate Cancer 306 // Andreas Wibmer, Irene A. Burger, and Hebert Alberto Vargas // 34 Somatostatin Receptor SPECT and PET Imaging: Protocols, Normal Findings, // Artifacts, and Pitfalls 317 // Harshad R. Kulkami and Richard P. Baum // 35 Bone-Seeking Tracers: [99mTc]Diphosphonate SPECT/CT // and [18F]Fluoride PET/CT 320 // Einat Even-Sapir Weizer // 36 SPECT and PET Imaging of the Thyroid: Protocols, Dosimetry, Normal Findings, Artifacts, and Pitfalls 326 // Andreas Bockisch, Walter fentzen, and Sandra Rosenbaum-Krumme // 37 Sentinel Node SPECT/CT Imaging for Tumor Staging: Protocols, Normal Findings, Artifacts, Pitfalls, and Clinical Applications 333 // Carina Mari Aparici, Youngho Seo, and Randall Hawkins // HEAD AND NECK TUMORS // 38 Head and Neck Cancer 341 // Martin W. Huellner, Felix P. Kuhn, and Hugh D. Curtin // 39 Tumors with an Unknown Primary (CUP) 362 // Martin W. Huellner and Hugh D. Curtin // 40 Thyroid Cancer 375 // Andreas Bockisch, Rainer Gorges, Lutz
Freudenberg, and Sandra Rosenbaum-Krumme // TUMORS OF THE THORAX // 41 Non-Small Cell Lung Cancer 383 // Lars Husmann, Paul Stolzmann, and Hans Steinert // 42 Small Cell Lung Cancer 392 // Lars Husmann, Paul Stolzmann, and Hans Steinert // 43 Malignant Pleural Mesothelioma 394 // Isabelle Opitz, Thomas Frauenfelder, and Patrick Veit-Haibach // 44 Mediastinal Tumors 400 // Lars Husmann, Bert-Ram Sah, and Paul Stolzmann // TUMORS OF THE GASTROINTESTINAL TRACT // 45 Esophageal and Gastric Cancers 403 // Patrick Veit-Haibach // 46 Malignant Tumors of the Hepatobiliary Tract and Pancreas 411 // Mi jin Yun // 47 Gastrointestinal Stromal Tumors 423 // Gerald Antoch // 48 Neuroendocrine Tumors 430 // Richard P. Baum, Harshad R. Kulkami, and Niklaus Schäfer // 49 Colorectal and Anal Carcinoma 438 // Cristina Nanni and Patrick Veit-Haibach // BREAST CANCER AND GENITOURINARY TUMORS // 50 Carcinoma of the Breast 451 // Richard L. Wahl // 51 Renal Tumors and Bladder Cancer 469 // Hossein Jadvar and Peter S. Conti // 52 Tumors of the Female Genital Tract 474 // Julie K. Schwarz, Kathryn J. Fowler, // Farrokh Deh dash ti, and Perry W. Grigsby // 53 Testicular Cancer 488 // Irene A. Burger and Hebert Alberto Vargas // 54 Prostate Cancer 494 // Werner Langsteger, Reza Vali, and Mohsen Beheshti // TÜÄtöRS OF BONE, JOINTS, MUSCLES, SKIN, // *>:: CONNECTIVE TISSUE // r : gnant Bone Tumors 503 // JL—rt F. Fun’ // 5 í ?-??? Metastases 509 // • - j : Even-Sapir Weizer // 5’ Befiign Bone Tumors
521 // \\ Strobel // 5 E Son Tissue Sarcomas 526 // F. Eary // 5 1 •.‘leianoma 537 // ’ ¦ Steinert, J il Dreier, Reinhard Dummer, // .y; j \\iklaiis Schäfer // n- MORS OF THE LYMPHATIC AND HEMOPOIETIC SYSTEMS // t Malignant Lymphoma 549 // ¦ -Lan Khong and Niklaus Schäfer // ž ’ jitiple Myeloma 562 // - . Nanni and Stefano Fanti // ; DIATION THERAPY // f 2 -adiation Oncology: Staging, Follow-Up, and Planning 567 // :ko Schöder, Andreas Rimner, and John Humm // PART VI • NONNEOPLASTIC DISEASE IN THE BODY // 6 3 Physiologic Basis of Inflammation maging 589 // \\:him H. Kaim and Gustav K. von Schulthess // 64 Soft Tissue Inflammation Including Vessels and Grafts 593 // Sabine Lardenoije, Chantal P. Bleeker-Rovers, and Wim J. G. Oyen // 65 Musculoskeletal Infections 604 // Klaus Strobel and Carsten Pietsch // 66 Infections in Patients with Orthopedic Implants 612 // Christopher Palestra // 67 Rheumatologie Disease 623 // Carsten Pietsch and Klaus Strobel // 68 Trauma 629 // Carsten Pietsch and Klaus Strobel // 69 Parathyroid and Benign Thyroid Disease 635 // Harvey A. Ziessman // 70 Pulmonary Thromboembolism 641 // Paul Stolzmann, Lars Husmann, and Hans Steinert // PART VII • CLINICAL HYBRID IMAGING IN PEDIATRIC PATIENTS // 71 Special Considerations in Pediatric Patients 647 // Lise Borgwardt, Anne Kiil Berthelsen, Annika Loft, and Liselotte Hojgaard // 72 Pediatric Whole-Body Oncology 653 // Annika Loft, Pek-Lan Khong, Lise Borgwardt, Anne Kiil Berthelsen, and Liselotte
Hojgaard // 73 Pediatric Inflammation and Other Nonneoplastic Diseases 660 // Lise Borgwardt and Liselotte Hojgaard // Index 669