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10th edition

New York ; London : W.W. Norton & Company, [2022]

xxii, 800 stran, 136 různě číslovaných stran : ilustrace (převážně barevné) ; 28 cm

ISBN 978-0-393-68093-5 (brožováno) ISBN !978-0-393-88491-3 (chyb.)

"International student edition"--Obálka

Terminologický slovník

Obsahuje bibliografie a rejstřík

001659467

Contents in Brief : PREFACE III // What’s new in the Tenth Edition iv // Resources for Instructors and Students vi // Acknowledgments vii // About  the Authors ix // PART I AN INTRODUCTION TO IMMUNOBIOLOGY AND INNATE IMMUNITY // Basic Concepts in Immunology 1 // Innate Immunity: The First Lines of Defense 37 // Cellular Mechanisms of Innate Immunity 79 // PART II THE RECOGNITION OF ANTIGEN // Antigen Recognition by B-cell and T-cell Receptors 141 // The Generation of Lymphocyte Antigen Receptors 179 // Antigen Presentation to T Lymphocytes 219 // PART III THE DEVELOPMENT OF MATURE LYMPHOCYTE RECEPTOR REPERTOIRES // ’ Lymphocyte Receptor Signaling 261 // The Development of B and T Lymphocytes 301 // PART IV THE ADAPTIVE IMMUNE RESPONSE // T Cell-Mediated Immunity 347 // The Humoral Immune Response 405 // Integrated Dynamics of Innate and Adaptive Immunity 453 // The Barrier Immune System 503 // PART V IMMUNE SYSTEM IN HEALTH AND DISEASE // Failures of Host Defense Mechanisms 587 // Allergic Diseases and Hypersensitivity Reactions 663 // Autoimmunity and Transplantation 699 // Manipulation of the Immune Response 749 // APPENDICES // Appendices ll-IV are available on digital.wwnorton.com/janeway10 and in the ebook. // I The Immunologist’s Toolbox // II CD Antigens // III Cytokines and Their Receptors // IV Chemokines and Their Receptors // Glossary // Credits // Index