.

0 (hodnocen0 x )

EB

ONLINE

Hoboken, N.J. : John Wiley & Sons, c2011

1 online resource (xiii, 377 p., [8] p. of plates) : ill. (some col.)

ISBN 9781118001035 (electronic bk.)

ISBN 9781118008980 (electronic bk.)

ISBN 9780470449820 (cloth)

ISBN 9781118001042 (oBook)

Includes bibliographical references and index

Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.

Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries

001728392

full

(Au-PeEL)EBL693202

(CaONFJC)MIL323966

(CaPaEBR)ebr10494674

(MiAaPQ)EBC693202

(OCoLC)746321023