.

0 (hodnocen0 x )

EB

ONLINE

Princeton, New Jersey : Princeton University Press, [2005]

1 online resource (384 pages) : illustrations

ISBN 9781400849383 (electronic bk.)

ISBN 0691122407 (cloth : alk. paper)

ISBN 9780691134048

aPrinceton studies in complexity

Print version: Wagner, Andreas. Robustness and evolvability in living systems. Princeton, New Jersey : Princeton University Press, [2005] xii, 367 pages ; 24 cm. Princeton studies in complexity ISBN 9780691134048

Includes bibliographical references (pages [323]-358) and index

Introduction -- The genetic alphabet -- The genetic code -- RNA structure -- Proteins and point mutations -- Proteins and recombination -- Regulatory DNA regions and their reorganization in evolution -- Metabolic pathways -- Metabolic networks -- Drosophila segmentation and other gene regulatory networks -- Phenotypic traits, cryptic variation, and human diseases -- The many ways of building the same body -- Neutral spaces -- Evolvability and neutral mutations -- Redundancy of parts or distributed robustness? -- Robustness as an evolved adaptation to mutations -- Robustness as an evolved adapatation to environmental change and noise -- Robustness and fragility: advantages to variation and trade-offs -- Robustness in natural systems and self-organization -- Robustness in man-made systems.

001765558

full

(Au-PeEL)EBL1422524

(CaONFJC)MIL530372

(CaPaEBR)ebr10782425

(MiAaPQ)EBC1422524

(OCoLC)860923072