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0 (hodnocen0 x )

EB

ONLINE

Second edition

Oxford : Oxford University Press, [2014]

1 online resource (328 pages) : illustrations

ISBN 9780199927548 (electronic bk.)

ISBN 9780199927531 (alk. paper)

Print version: Migeon, Barbara R. Females are mosaics : X inactivation and sex differences in disease. Oxford : Oxford University Press, [2014] xviii, 307 pages ISBN 9780199927531

Includes bibliographical references and index

Sex differences in disease -- Evolution of the human sex chromosomes and a portrait of the human X -- X chromosome dosage compensation : an overview -- The discovery of X chromosome inactivation -- Experimental models for X inactivation studies -- Theme 1 : the initial step : creating the active and inactive X -- Theme 2 : subsequent steps : spreading and maintaining inactivation -- Variations 1 : evolution of the X inactivation center -- Variations 2 : stability of the inactive X -- Variations 3 : choice of active X -- The single active X -- Mosaicism -- Epimutations, chromatin disorders and sex differences in phenotype -- Determinants of female phenotypes.

001766738

full

(Au-PeEL)EBL1481007

(CaONFJC)MIL525298

(CaPaEBR)ebr10775462

(MiAaPQ)EBC1481007

(OCoLC)859536749