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0 (hodnocen0 x )

BK

Sixth edition

[Amsterdam?] : Elsevier, 2022

xxiv, 720 stran : barevné ilustrace ; 28 cm

ISBN 978-0-323-83450-6 (brožováno)

Obsahuje bibliografie a rejstřík

002002135

List of Contributors ...vii // Acknowledgments ...xi // Dedication ...xiii // Preface ...xv // Abbreviations ...xvii // SECTION 1 Introduction // 1 Biochemistry and Clinical Medicine: Introduction and Overview ...1 - John W. Baynes and Marek H. Dominiczak // SECTION 2 Molecules and Cells // 2 Amino Acids and Proteins ...9 - Ryoji Nagai // 3 Carbohydrates and Lipids ...25 - John W. Baynes // 4 Membranes and Transport ...37 - Masatomo Maeda // SECTION 3 Metabolism // 5 Oxygen Transport ...49 - John W. Baynes and Norma Frizzell // 6 Catalytic Proteins - Enzymes - Junichi Fujii // 7 Vitamins and Minerals ...79 - Marek H. Dominiczak // 8 Bioenergetics and Oxidative Metabolism ...95 - Norma Frizzell // 9 Glycolysis and the Pentose Phosphate Pathway ...115 // 10 The Tricarboxylic Acid Cycle ...129 - Norma Frizzell // 11 Fatty Acid and Triglyceride Catabolism ...143 - John W. Baynes // 12 Biosynthesis and Storage of Carbohydrate ...153 - John W. Baynes // 13 Biosynthesis and Storage of Fatty Acids ...171 - Fredrik Karpe and Iain Broom // 14 Biosynthesis of Cholesterol and Steroids ...181 - Marek H. Dominiczak // 15 Biosynthesis and Degradation of Amino Acids ...197 - Allen B. Rawitch and John W. Baynes // 16 Biosynthesis änd Degradation of Nucleotides ...213 - Aleiandro Guqliucci and Teresita Menini // 17 Complex Carbohydrates: Glycoproteins ...225 - Koichi Honke // 18 Complex Lipids ...243 - Koichi Honke // 19 The Extracellular Matrix ...255 - Wayne E. Carver // SECTION 4 Molecular Basis of Inheritance // 20 Deoxyribonucleic Acid ...269 - Alejandro Gugliucci and Teresita Menini // 21 Ribonucleic Acid ...289 - Robert W. Thornburg // 22 Protein Synthesis and Turnover ...303 - Edel M. Hyland // 23 Regulation of Gene Expression: Basic Mechanisms ...317 - Edel M. Hyland // 24 Genomics, Proteomics and Metabolomics ...333 - Andrew R. Pitt and Walter Kolch // SECTION 5 Signalling and Growth //

25 Membrane Receptors and Signal Transduction ...359 - Ian P. Salt and Sophie J. Bradley // 26 Neurotransmitters ...375 - Simon Pope and Simon J. R. Heales // 27 Biochemical Endocrinology ...391 - David Church. Robert Semple and Marek H. Dominiczak ’ // 28 Cellular Homeostasis: Cell Growth and Cancer ...423 - Alison M. Michie, Verica Paunovic, and Margaret M. Harnett // 29 Aging ...443 - John W. Haynes // SECTION 6 Fuels Nutrients and Minerals // 30 Digestion and Absorption of Nutrients: The Gastrointestinal Tract ...455 - Marek H. Dominiczak and Matthew Priest // 31 Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus ...471 - Marek H. Dominiczak // 32 Nutrients and Diets ...501 - Marek H. Dominiczak and Jennifer Logue // 33 Lipoprotein Metabolism and Atherogenesis ...519 - Marek H. Dominiczak // SECTION 7 Specialized Tissues and Their Function // 34 Role of Liver in Metabolism ...539 - Alan F. Jones and Marek H. Dominiczak // 35 Water and Electrolytes Homeostasis ...555 - Marek H. Dominiczak // 36 The Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance) ...573 - Marek H. Dominiczak and Mirosława Szczepatiska-Konkel // 37 Muscle: Energy Metabolism, Contraction, and Exercise ...585 - Matthew C. Kostek // 38 Bone Metabolism and Calcium Homeostasis ...599 - William Fraser and Marek H. Dominiczak // 39 Neurochemistry ...613 - Marek H. Dominiczak // SECTION 8 Blood and Immunity. Clinical Biochemistry // 40 Blood and Plasma Proteins ...625 - Marek H. Dominiczak // 41 Hemostasis and Thrombosis ...635 - Catherine N. Batjot // 42 Oxidative Stress and Inflammation ...651 - John W. Baynes // 43 The Immune Response: Innate and Adaptive Immunity ...663 - Georgia Perona-Wright and ]. Alastair Grade // Appendix 1: Selected Clinical Laboratory Reference Ranges ....683 - Yee Piny Teoh and Marek H. Dominiczak // Index ...693