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0 (hodnocen0 x )

BK

Fifth edition

[Philadelphia] : Elsevier, 2019

xxvi, 682 stran : barevné ilustrace ; 28 cm

ISBN 978-0-7020-7299-4 (brožováno)

Obsahuje bibliografie a rejstřík

001465207

Contents // List of Contributors ix // Acknowledgments xiii // Dedication xv // Preface xvii // Abbreviations xix // SECTION 1 - Introduction // 1 Introduction 1 - John W. Baynes, Marek H. Dominiczak // SECTION 2 - Molecules and Cells // 2 Amino Acids and Proteins 7 - Ryoji Nagai, Naoyuki Taniguchi // 3 Carbohydrates and Lipids 25 - John W. Baynes // 4 Membranes and Transport 35 - John W. Baynes, Masatomo Maeda // SECTION 3 - Metabolism // 5 Oxygen Transport 47 - John W. Baynes, Norma Frizzell, George M. Helmkamp Jr. // 6 Catalytic Proteins - Enzymes 61 - Junichi Fujii // 7 Vitamins and Minerals 75 - Marek H. Dominiczak // 8 Bioenergetics and Oxidative Metabolism 93 - Norma Frizzell, L. William Stillway // 9 Anaerobic Metabolism of Carbohydrates in the Red Blood Cell 111 - John W. Baynes // 10 The Tricarboxylic Acid Cycle 125 - Norma Frizzell, L. William Stillway // 11 Oxidative Metabolism of Lipids in Liver and Muscle 137 - John W. Baynes // 12 Biosynthesis and Storage of Carbohydrate in Liver and Muscle 147 - John W. Baynes // 13 Biosynthesis and Storage of Fatty Acids 163 - Fredrik Karpe, Iain Broom // 14 Biosynthesis of Cholesterol and Steroids 173 - Marek H. Dominiczak // 15 Biosynthesis and Degradation of Amino Acids 187 - Allen B. Rawitch // 16 Biosynthesis and Degradation of Nucleotides 202 - Alejandro Gugliucci, Robert W. Thornburg Teresita Menini // 17 Complex Carbohydrates: Glycoproteins 215 - Alan D. Elbein (deceased), Koichi Honke // 18 Complex Lipids 231 Alan D. Elbein (deceased), Koichi Honke // 19 The Extracellular Matrix 243 - Gur P. Kaushal, Alan D. Elbein (deceased), Wayne E. Carver // SECTION 4 - Molecular Basis of Inheritance // 20 Deoxyribonucleic Acid 257 - Alejandro Gugliucci, Robert W. Thornburg, Teresita Menini // 21 Ribonucleic Acid 275 - Robert W. Thornburg // 22 Protein Synthesis and Turnover 289 - Edel M. Hyland Jeffrey R. Patton //

23 Regulation of Gene Expression: Basic Mechanisms 303 - Edel M. Hyland, Jeffrey R. Patton // 24 Genomics, Proteomics, and Metabolomics 319 - Andrew R. Pitt, Walter Kolch // SECTION 5 - Signaling and Growth // 25 Membrane Receptors and Signal Transduction 339 - Ian P. Salt // 26 Neurotransmitters 355 - Simon Pope, Simon J. R. Heales // 27 Biochemical Endocrinology 369 - David Church, Robert Semple // 28 Cellular Homeostasis: Cell Growth and Cancer 397 - Alison M. Michie, Verica Paunovic, Margaret M. Harnett // 29 Aging 417 - John W. Baynes // SECTION 6 - Fuels Nutrients and Minerals // 30 Digestion and Absorption of Nutrients: The Gastrointestinal Tract 429 - Marek H. Dominiczak, Matthew Priest // 31 Glucose Homeostasis and Fuel Metabolism: Diabetes Mellitus 443 - Marek H. Dominiczak // 32 Nutrients and Diets 471 - Marek H. Dominiczak, Jennifer Logue // 33 Lipoprotein Metabolism and Atherogenesis 489 - Marek H. Dominiczak // SECTION 7 - Specialized Tissues and Their Function // 34 Role of the Liver in Metabolism 507 - Alan F. Jones // 35 Water and Electrolytes Homeostasis 523 - Marek H. Dominiczak, Mirosława Szczepańska-Konkel // 36 The Lung and the Regulation of Hydrogen Ion Concentration (Acid-Base Balance) 539 - Marek H. Dominiczak, Mirosława Szczepańska-Konkel // 37 Muscle: Energy Metabolism, Contraction, and Exercise 551 - John W. Baynes, Matthew C. Kostek // 38 Bone Metabolism and Calcium Homeostasis 565 - Marek H. Dominiczak // 39 Neurochemistry 577 - Hanna Bielarczyk, Andrzej Szutowicz // SECTION 8 - Blood and Immunity. Clinical Biochemistry // 40 Blood and Plasma Proteins 589 - Marek H. Dominiczak // 41 Hemostasis and Thrombosis 599 - Catherine N. Bagot // 42 Oxidative Stress and Inflammation 615 - John W. Baynes // 43 The Immune Response: Innate and Adaptive Immunity 627 - J. Alistair Grade, Georgia Perona-Wright //

Appendix 1: Selected Clinical Laboratory Reference Ranges 647 - Yee Ping Teoh, Marek H. Dominiczak // Appendix 2: More Clinical Cases 657 - Susan Johnston // Index 661