Contents // Preface ix // Acknowledgements xii ntroduction 1 // Asking answerable clinical questions 19 // Acquiring the evidence: How to find current best evidence and have current best evidence find us 35 // Appraising the evidence 67 // Therapy 71 // Diagnosis and screening 153 Prognosis 185 Harm 201 Evaluation 223 // ’eaching evidence-based medicine 237 // -opendix 1 : Glossary 299 // -apendix 2: Confidence intervals (ebook only) e1 // index 309 // v