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BK

4th edition

Lyon : International Agency for Research on Cancer, 2015

412 stran : barevné ilustrace ; 27 cm

ISBN 978-92-832-2436-5 (brožováno)

World Health Organization classification of tumours

Nad názvem: WHO, OMS, International Agency for Research on Cancer (IARC)

Obsahuje bibliografii na stranách 366-404 a rejstřík

001484801

Contents // 1 Tumours of the lung 9 // WHO and TNM classifications 10 // Lymph node stations 12 // Lung cancer staging and grading 14 // Rationale for classification in small biopsies and cytology 16 Terminology and criteria in non-resection specimens 17 // Molecular testing for treatment selection in lung cancer 22 // Adenocarcinoma 26 // Lepidic adenocarcinoma 34 // Acinar adenocarcinoma 34 // Papillary adenocarcinoma 35 // Micropapillary adenocarcinoma 35 // Solid adenocarcinoma 35 // Invasive mucinous adenocarcinoma 38 // Mixed invasive mucinous and non-mucinous // adenocarcinoma 38 // Colloid adenocarcinoma 40 // Petal adenocarcinoma 41 // Enteric adenocarcinoma 42 // Minimally invasive adenocarcinoma 44 // Preinvasive lesions 46 // Atypical adenomatous hyperplasia 46 // Adenocarcinoma in situ 48 // Squamous cell carcinoma 51 // Keratinizing 51 // Non-keratinizing 51 // Basaloid squamous cell carcinoma 56 // Preinvasive lesion 59 // Squamous cell carcinoma in situ 59 // Neuroendocrine tumours 63 // Small cell carcinoma 63 // Large cell neuroendocrine carcinoma 69 // Carcinoid tumour 73 // Diffuse idiopathic pulmonary // neuroendocrine cell hyperplasia 78 // Large cell carcinoma 80 // Adenosquamous carcinoma 86 // Sarcomatoid carcinoma 88 // Pleomorphic, spindle cell, and giant cell carcinoma 88 // Carcinosarcoma 91 // Pulmonary blastoma 93 // Other and unclassified carcinomas 95 // Lymphoepithelioma-like carcinoma 95 // NUT carcinoma 97 // Salivary gland-type tumours 99

Mucoepidermoid carcinoma 99 // Adenoid cystic carcinoma 101 // Epithelial-myoepithelial carcinoma 103 // Pleomorphic adenoma 105 // Papillomas 106 // Squamous cell papilloma 106 // Glandular papilloma 108 // Mixed squamous cell and glandular papilloma 108 // Adenomas 110 // Sclerosing pneumocytoma 110 // Alveolar adenoma 112 // Papillary adenoma 113 // Mucinous cystadenoma 114 // Mucous gland adenoma 115 // Mesenchymal tumours 116 // Pulmonary hamartoma 116 // Chondroma 117 // PEComatous tumours 117 // Congenital peribronchial myofibroblastic tumour 119 // Diffuse pulmonary lymphangiomatosis 121 // Inflammatory myofibroblastic tumour 121 // Epithelioid haemangioendothelioma 123 // Pleuropulmonary blastoma 124 // Synovial sarcoma 127 // Pulmonary artery intimal sarcoma 128 // Pulmonary myxoid sarcoma with EWSR1-CREB1 // translocation 129 // Myoepithelial tumours / myoepithelial carcinoma 131 // Other mesenchymal tumours 132 // Lymphohistiocytic tumours 134 // Extranodal marginal zone lymphoma of mucosa- // associated lymphoid tissue (MALT lymphoma) 134 // Diffuse large В-cell lymphoma 136 // Lymphomatoid granulomatosis 138 // Intravascular large В-cell lymphoma 140 // Pulmonary Langerhans cell histiocytosis 141 // Erdheim-Chester disease 142 // Tumours of ectopic origin 144 // Germ cell tumours 144 // Intrapulmonary thymoma 145 // Melanoma 146 // Meningioma 147 // Metastases to the lung 148 // 2 Tumours of the pleura 153 // WHO and TNM classifications 154 // Mesothelial tumours 156

// Diffuse malignant mesothelioma 156 // Epithelioid mesothelioma 156 // Sarcomatoid, desmoplastic, and biphasic // mesothelioma 165 // Localized malignant mesothelioma 169 // Well-differentiated papillary mesothelioma 170 // Adenomatoid tumour 171 // Lymphoproliferative disorders 172 // Primary effusion lymphoma 172 // Diffuse large В-cell lymphoma associated with chronic inflammation 174 // Mesenchymal tumours 176 // Epithelioid haemangioendothelioma 176 // Angiosarcoma 177 // Synovial sarcoma 177 // Solitary fibrous tumour 178 // Desmoid-type fibromatosis 179 // Calcifying fibrous tumour 180 // Desmoplastic round cell tumour 180 // 3 Tumours of the thymus 183 // WHO classification 184 // TNM classifications 186 // Thymomas 187 // Type A thymoma, including atypical variant 187 // Type AB thymoma 193 // Type B1 thymoma 196 // Type B2 thymoma 199 // Type B3 thymoma 202 // Micronodular thymoma with lymphoid stroma 205 // Metaplastic thymoma 207 // Other rare thymomas 209 // Microscopic thymoma 209 // Sclerosing thymoma 210 // Lipotibroadenoma 210 // Thymic carcinomas 212 // Squamous cell carcinoma 212 // Basaloid carcinoma 216 // Mucoepidermoid carcinoma 218 // Lymphoepithelioma-like carcinoma 220 // Clear cell carcinoma 222 // Sarcomatoid carcinoma 224 // Adenocarcinomas 226 // NUT carcinoma 229 // Undifferentiated carcinoma 232 // Other rare thymic carcinomas 233 // Thymic neuroendocrine tumours 234 // Typical and atypical carcinoids 234 // Typical carcinoid 234 // Atypical

carcinoid 237 // Large cell neuroendocrine carcinoma 239 // Small cell carcinoma 241 // Combined thymic carcinomas 242 // Germ cell tumours of the mediastinum 244 // Seminoma 244 // Embryonal carcinoma 249 // Yolk sac tumour 251 // Choriocarcinoma 255 // Mature and immature teratoma 257 // Mixed germ cell tumours 260 // Germ cell tumours with somatic-type solid malignancy 263 // Germ cell tumours with associated // haematological malignancy 265 // Lymphomas of the mediastinum 267 // Primary mediastinal large В-cell lymphoma 267 // Extranodal marginal zone lymphoma of mucosa- // associated lymphoid tissue (MALT lymphoma) 270 // Other mature В cell lymphomas 272 // T lymphoblastic leukaemia / lymphoma 272 // Anaplastic large cell lymphoma and other rare // mature T- and NK-cell lymphomas 275 // Hodgkin lymphoma 277 // В-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma 280 // Histiocytic and dendritic cell neoplasms // of the mediastinum 282 // Langerhans cell lesions 282 // Histiocytic sarcoma 283 // Follicular dendritic cell sarcoma 284 // Interdigitating dendritic cell sarcoma 285 // Fibroblastic reticular cell tumour 286 // Other dendritic cell tumours 287 // Myeloid sarcoma and extramedullary acute // myeloid leukaemia 288 // Soft tissue tumours of the mediastinum 289 // Thymolipoma 289 // Lipoma 290 // Liposarcoma 290 // Solitary fibrous tumour 291 // Synovial sarcoma 291 // Vascular neoplasms 292

// Neurogenic tumours 293 // Ganglioneuroma, ganglioneuroblastoma, and // neuroblastoma 294 // Other rare mesenchymal tumours 295 // Ectopic tumours of the thymus 296 // Ectopic thyroid tumours 296 // Ectopic parathyroid tumours 296 // Other rare ectopic tumours 297 // Metastasis to the thymus or mediastinum 298 // 4 Tumours of the heart 299 // WHO classification 300 // Introduction 301 // Benign tumours and tumour-like lesions 305 // Rhabdomyoma 305 // Histiocytoid cardiomyopathy 307 // Hamartoma of mature cardiac myocytes 309 // Adult cellular rhabdomyoma 310 // Cardiac myxoma 311 // Papillary fibroelastoma 315 // Haemangioma 318 // Cardiac fibroma 320 // Lipoma 322 // Cystic tumour of the atrioventricular node 323 // Granular cell tumour 324 // Schwannoma 325 // Tumours of uncertain behaviour 326 // Inflammatory myofibroblastic tumour 326 // Paraganglioma 326 // Germ cell tumours 327 // Teratoma, mature 327 // Teratoma, immature 327 // Yolk sac tumour 327 // Malignant tumours 329 // Angiosarcoma 329 // Undifferentiated pleomorphic sarcoma 331 // Osteosarcoma 333 // Myxofibrosarcoma 334 // Leiomyosarcoma 336 // Rhabdomyosarcoma 337 // Synovial sarcoma 338 // Miscellaneous sarcomas 339 // Cardiac lymphomas 340 // Metastatic tumours 342 // Tumours of the pericardium 344 // Solitary fibrous tumour 344 // Sarcomas 344 // Malignant mesothelioma 345 // Germ cell tumours 346 // Metastatic tumours 347 // Contributors 349 // IARC/WHO Committee for ICD-0 359 // Sources of figures and tables 360 // References 366 // Subject index 405 // List of abbreviations 412