.

0 (hodnocen0 x )

EB

ONLINE

Hoboken, N.J. : Wiley, 2013

1 online resource (xv, 552 p., [16] p. of plates) : ill. (some col.)

ISBN 9781118538180 (electronic bk.)

ISBN 9781118065631 (hardback)

Includes bibliographical references and index

pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe’s REACH legislation and the US National Research Council"-- Provided by publisher..

Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries

001755406

full

(Au-PeEL)EBL1129737

(CaONFJC)MIL456509

(CaPaEBR)ebr10662545

(MiAaPQ)EBC1129737

(OCoLC)828868892