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0 (hodnocen0 x )

EB

ONLINE

Philadelphia : Wolters Kluwer Health, 2020

1 online resource (724 pages)

ISBN 9781496375568 (electronic bk.)

ISBN 9781496375544

Print version: Duffield, Amy S. Atlas of Lymph Node Pathology Philadelphia : Wolters Kluwer Health,c2020 ISBN 9781496375544

Intro -- Title page -- Copyright -- Dedication -- Preface -- Contributors -- Contents -- 1. INTRODUCTION TO THE LYMPH NODE -- Lymph Node Structure -- Capsule -- Sinuses -- Cortex -- Paracortex -- Medulla -- Specimen Preparation -- Fixation -- Frozen Sections -- Limited Specimens -- Clinical Context -- Anatomic Site -- Patient Demographics -- Clinical Information -- Ancillary Studies -- Flow Cytometry -- Cytogenetic/FISH Studies -- Molecular Studies -- Near Misses -- IgG4-Reactive Lymphadenopathy -- Nodal Marginal Zone B-Cell Lymphoma With Colonization of Reactive Follicles -- Intrafollicular Neoplasia -- Interfollicular Classical Hodgkin Lymphoma -- Early Angioimmunoblastic T-cell Lymphoma -- 2. THE LYMPH NODE CAPSULE -- Normal Lymph Node Capsule -- Absent Capsule -- Lymph Node Versus Lymphoid Tissue -- Capsular Inclusions -- Disrupted Capsule -- Thickened Capsule -- Reactive Conditions -- Neoplastic Conditions -- Near Misses -- Angioimmunoblastic T-cell Lymphoma -- Kaposi Sarcoma -- Tumor-Infiltrating Lymphocytes Versus Metastatic Disease -- Capsular Nevi Versus Metastatic Melanoma -- 3. THE LYMPHATIC SINUSES -- Introduction -- Conditions With Dilated Prominent Sinuses -- Sinus Histiocytosis and Dermatopathic Lymphadenopathy -- Sinus Histiocytosis With Massive Lymphadenopathy (SHML) -- Langerhans Cell Histiocytosis (LCH) -- Lymphoplasmacytic Lymphoma -- Node Draining Suppurative Area -- Lipid-Associated Lymphadenopathy (Lymphangiogram, Prosthesis, or Storage Diseases) -- Vascular Transformation of Sinuses -- Near Miss -- Sinusoidal Involvement by Kaposi Sarcoma Mimicking Vascular Transformation of Sinuses -- Sinusoidal Lymphomatous Infiltrates -- Near Miss -- ALCL Mimicking Metastatic Carcinoma -- Metastatic Cancer -- Near Miss -- Benign Mesothelial Cells -- Leukemic Infiltrates -- Other Perisinusoidal Cellular Clusters.

Conditions With Inconspicuous/Obliterated Sinuses -- Follicular Lymphoma -- Castleman Disease -- Angioimmunoblastic T-cell Lymphoma -- 4. CORTEX -- Introduction -- Clinical Correlation -- Site-Specific Variations in Follicles -- Abnormal Follicles -- Reactive Follicular Hyperplasia -- Giant Follicular Hyperplasia -- Reactive Follicular Hyperplasia In Altered Immune States -- Intrafollicular Plasmacytosis-IgG4 Disease -- Other Clonal Conditions With Reactive Hyperplasia -- Abnormal Expanded Mantle Zones -- Castleman-Like Proliferations -- Progressive Transformation of Germinal Centers -- Kimura Disease -- Attenuated Mantle Zones -- Other Infectious Processes -- Toxoplasma -- 5. PARACORTEX -- Paracortical Hyperplasia -- Dermatopathic Lymphadenopathy -- Infection -- Drug-Associated Lymphadenopathy -- Autoimmune Conditions -- Systemic Lupus Erythematosus Lymphadenopathy -- Atypical Paracortical Hyperplasia -- Histiocytic Proliferations -- Singly/Small Clusters -- Granulomas -- Extensive/Diffuse -- Vascular Changes -- Vascular Proliferation -- Abnormalities of Vessel Walls -- Expansion/Infiltration of the Paracortex by Unexpected Cells -- Atypical Lymphocytes/Lymphomas -- Plasma Cells -- Spindled Cells -- Necrosis -- Near Misses -- Hamazaki-Wesenberg Bodies in Sarcoidosis Lymphadenopathy -- Indolent T-Lymphoblastic Proliferation -- Lymph Node Involvement by Myeloid/Lymphoid Neoplasms With PDGFRA Rearrangement -- 6. OBLITERATED NODULAR PATTERN -- Introduction -- List of Entities to Consider in Cases With Nodular Pattern -- Follicular lymphoma -- Some Histologic Variations That Represent Pitfalls in the Diagnosis of Follicular Lymphoma -- Grading and Follicular Lymphoma -- Unconventional Wisdom Relating to FL Grading -- Immunostains and Approach in Nodular Proliferations.

T-Cell and NK Cell Lymphoma -- Peripheral T-Cell Lymphoma, Not Otherwise Specified -- NK/T-Cell Lymphoma -- Anaplastic Large Cell Lymphoma -- Infectious Etiologies -- Mycobacterial Lymphadenitis -- Cytomegalovirus Infection -- Herpes Simplex Lymphadenitis -- Cat Scratch Disease -- Fungal Infection/Lymphadenitis -- Benign Reactive Lymphoproliferative Disorders -- Systemic Lupus Erythematosus -- Near Misses -- Epstein-Barr Virus: Infectious Mononucleosis -- Kikuchi-Fujimoto Lymphadenitis -- 9. IMMUNOHISTOCHEMISTRY -- Introduction -- Key Features Related to Technical Points in Immunohistochemistry -- List of Common Antibodies in Lymphoma Immunohistochemistry -- Near Miss -- CD20-Negative Follicular Lymphoma -- Incidental Mantle Cell Lymphoma in Reactive Looking Node -- Peripheral T-cell Lymphoma With Hodgkin-Like Cells of B-Cell Derivation -- Stains Related to Microorganisms -- Extracavitary Primary Effusion Lymphoma -- Exercise in Interpretation, Sample Write-Ups in One Single Case, and Best Practices in Write-Ups -- SELF-ASSESSMENT QUESTIONS -- SELF-ASSESSMENT ANSWERS -- INDEX.

Scenarios and Clinical Details That Determine How You Look at and Sign Out Some Follicular Lymphoma Cases -- Pitfall Cases of Nodular Proliferations -- Pitfall Case 1: Nodal Marginal Zone lymphoma with Follicular Colonization -- Pitfall Case 2: Germinotropic lymphoproliferative disorder, EBV+/ HHV8+ -- Pitfall Case 3: Follicular variant of peripheral T-cell lymphoma (Figures 6.66-6.70) -- 7. OBLITERATED NODAL ARCHITECTURE -- B-Cell Lymphomas -- Small Lymphocytic Lymphoma and Richter Syndrome -- Mantle Cell Lymphoma -- Diffuse Follicular Lymphoma -- Follicular Lymphoma With Transformation to DLBCL -- Plasmacytoma/Plasma Cell Myeloma -- Diffuse Large B-Cell Lymphoma, Not Otherwise Specified -- T-Cell-/Histiocyte-Rich Large B-Cell Lymphoma -- Plasmablastic Lymphoma -- Primary Mediastinal Large B-Cell Lymphoma -- B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma (Gray Zone Lymphoma) -- Burkitt Lymphoma -- High-Grade B-Cell Lymphoma -- T-Cell Lymphomas -- Anaplastic Large-Cell Lymphoma -- Peripheral T-Cell Lymphoma -- Lymphoepithelioid Variant of PTCL (Lennert Lymphoma) -- Precursor Lesion -- Myeloid Sarcoma -- B-Lymphoblastic Lymphoma -- T-Lymphoblastic Lymphoma -- Near Misses -- Blastoid Variant of Mantle Cell Lymphoma -- Nodal Involvement by CD30-Positive T-Cell Lymphoproliferative Disorder -- Peripheral T-Cell Lymphoma With Hodgkin-Like Cells -- Anaplastic Large-Cell Lymphoma With Aberrant Expression of PAX -- 8. NECROSIS -- Introduction -- Lymphoma/Aggressive Lymphoproliferative Neoplasms -- B-Cell Lymphoma -- B Lymphoblastic Lymphoma -- Diffuse Large B-Cell Lymphoma, Not Otherwise Specified -- EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified -- Post-Transplant Lymphoproliferative Disorder -- Plasmablastic Lymphoma -- Classical Hodgkin Lymphoma.

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